Class EffectEvidenceSynthesis.Builder

    • Method Detail

      • id

        public EffectEvidenceSynthesis.Builder id​(String id)
        The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.
        Overrides:
        id in class DomainResource.Builder
        Parameters:
        id - Logical id of this artifact
        Returns:
        A reference to this Builder instance
      • meta

        public EffectEvidenceSynthesis.Builder meta​(Meta meta)
        The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.
        Overrides:
        meta in class DomainResource.Builder
        Parameters:
        meta - Metadata about the resource
        Returns:
        A reference to this Builder instance
      • implicitRules

        public EffectEvidenceSynthesis.Builder implicitRules​(Uri implicitRules)
        A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.
        Overrides:
        implicitRules in class DomainResource.Builder
        Parameters:
        implicitRules - A set of rules under which this content was created
        Returns:
        A reference to this Builder instance
      • text

        public EffectEvidenceSynthesis.Builder text​(Narrative text)
        A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.
        Overrides:
        text in class DomainResource.Builder
        Parameters:
        text - Text summary of the resource, for human interpretation
        Returns:
        A reference to this Builder instance
      • contained

        public EffectEvidenceSynthesis.Builder contained​(Resource... contained)
        These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Overrides:
        contained in class DomainResource.Builder
        Parameters:
        contained - Contained, inline Resources
        Returns:
        A reference to this Builder instance
      • contained

        public EffectEvidenceSynthesis.Builder contained​(Collection<Resource> contained)
        These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Overrides:
        contained in class DomainResource.Builder
        Parameters:
        contained - Contained, inline Resources
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • extension

        public EffectEvidenceSynthesis.Builder extension​(Extension... extension)
        May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Overrides:
        extension in class DomainResource.Builder
        Parameters:
        extension - Additional content defined by implementations
        Returns:
        A reference to this Builder instance
      • extension

        public EffectEvidenceSynthesis.Builder extension​(Collection<Extension> extension)
        May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Overrides:
        extension in class DomainResource.Builder
        Parameters:
        extension - Additional content defined by implementations
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • modifierExtension

        public EffectEvidenceSynthesis.Builder modifierExtension​(Extension... modifierExtension)
        May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

        Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Overrides:
        modifierExtension in class DomainResource.Builder
        Parameters:
        modifierExtension - Extensions that cannot be ignored
        Returns:
        A reference to this Builder instance
      • modifierExtension

        public EffectEvidenceSynthesis.Builder modifierExtension​(Collection<Extension> modifierExtension)
        May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

        Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Overrides:
        modifierExtension in class DomainResource.Builder
        Parameters:
        modifierExtension - Extensions that cannot be ignored
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • url

        public EffectEvidenceSynthesis.Builder url​(Uri url)
        An absolute URI that is used to identify this effect evidence synthesis when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this effect evidence synthesis is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the effect evidence synthesis is stored on different servers.
        Parameters:
        url - Canonical identifier for this effect evidence synthesis, represented as a URI (globally unique)
        Returns:
        A reference to this Builder instance
      • identifier

        public EffectEvidenceSynthesis.Builder identifier​(Identifier... identifier)
        A formal identifier that is used to identify this effect evidence synthesis when it is represented in other formats, or referenced in a specification, model, design or an instance.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        identifier - Additional identifier for the effect evidence synthesis
        Returns:
        A reference to this Builder instance
      • identifier

        public EffectEvidenceSynthesis.Builder identifier​(Collection<Identifier> identifier)
        A formal identifier that is used to identify this effect evidence synthesis when it is represented in other formats, or referenced in a specification, model, design or an instance.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        identifier - Additional identifier for the effect evidence synthesis
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • version

        public EffectEvidenceSynthesis.Builder version​(String version)
        The identifier that is used to identify this version of the effect evidence synthesis when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the effect evidence synthesis author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.
        Parameters:
        version - Business version of the effect evidence synthesis
        Returns:
        A reference to this Builder instance
      • name

        public EffectEvidenceSynthesis.Builder name​(String name)
        A natural language name identifying the effect evidence synthesis. This name should be usable as an identifier for the module by machine processing applications such as code generation.
        Parameters:
        name - Name for this effect evidence synthesis (computer friendly)
        Returns:
        A reference to this Builder instance
      • title

        public EffectEvidenceSynthesis.Builder title​(String title)
        A short, descriptive, user-friendly title for the effect evidence synthesis.
        Parameters:
        title - Name for this effect evidence synthesis (human friendly)
        Returns:
        A reference to this Builder instance
      • status

        public EffectEvidenceSynthesis.Builder status​(PublicationStatus status)
        The status of this effect evidence synthesis. Enables tracking the life-cycle of the content.

        This element is required.

        Parameters:
        status - draft | active | retired | unknown
        Returns:
        A reference to this Builder instance
      • date

        public EffectEvidenceSynthesis.Builder date​(DateTime date)
        The date (and optionally time) when the effect evidence synthesis was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the effect evidence synthesis changes.
        Parameters:
        date - Date last changed
        Returns:
        A reference to this Builder instance
      • publisher

        public EffectEvidenceSynthesis.Builder publisher​(String publisher)
        The name of the organization or individual that published the effect evidence synthesis.
        Parameters:
        publisher - Name of the publisher (organization or individual)
        Returns:
        A reference to this Builder instance
      • contact

        public EffectEvidenceSynthesis.Builder contact​(ContactDetail... contact)
        Contact details to assist a user in finding and communicating with the publisher.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        contact - Contact details for the publisher
        Returns:
        A reference to this Builder instance
      • contact

        public EffectEvidenceSynthesis.Builder contact​(Collection<ContactDetail> contact)
        Contact details to assist a user in finding and communicating with the publisher.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        contact - Contact details for the publisher
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • description

        public EffectEvidenceSynthesis.Builder description​(Markdown description)
        A free text natural language description of the effect evidence synthesis from a consumer's perspective.
        Parameters:
        description - Natural language description of the effect evidence synthesis
        Returns:
        A reference to this Builder instance
      • note

        public EffectEvidenceSynthesis.Builder note​(Annotation... note)
        A human-readable string to clarify or explain concepts about the resource.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        note - Used for footnotes or explanatory notes
        Returns:
        A reference to this Builder instance
      • note

        public EffectEvidenceSynthesis.Builder note​(Collection<Annotation> note)
        A human-readable string to clarify or explain concepts about the resource.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        note - Used for footnotes or explanatory notes
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • useContext

        public EffectEvidenceSynthesis.Builder useContext​(UsageContext... useContext)
        The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        useContext - The context that the content is intended to support
        Returns:
        A reference to this Builder instance
      • useContext

        public EffectEvidenceSynthesis.Builder useContext​(Collection<UsageContext> useContext)
        The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        useContext - The context that the content is intended to support
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • jurisdiction

        public EffectEvidenceSynthesis.Builder jurisdiction​(CodeableConcept... jurisdiction)
        A legal or geographic region in which the effect evidence synthesis is intended to be used.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        jurisdiction - Intended jurisdiction for effect evidence synthesis (if applicable)
        Returns:
        A reference to this Builder instance
      • jurisdiction

        public EffectEvidenceSynthesis.Builder jurisdiction​(Collection<CodeableConcept> jurisdiction)
        A legal or geographic region in which the effect evidence synthesis is intended to be used.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        jurisdiction - Intended jurisdiction for effect evidence synthesis (if applicable)
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • copyright

        public EffectEvidenceSynthesis.Builder copyright​(Markdown copyright)
        A copyright statement relating to the effect evidence synthesis and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the effect evidence synthesis.
        Parameters:
        copyright - Use and/or publishing restrictions
        Returns:
        A reference to this Builder instance
      • approvalDate

        public EffectEvidenceSynthesis.Builder approvalDate​(Date approvalDate)
        The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage.
        Parameters:
        approvalDate - When the effect evidence synthesis was approved by publisher
        Returns:
        A reference to this Builder instance
      • lastReviewDate

        public EffectEvidenceSynthesis.Builder lastReviewDate​(Date lastReviewDate)
        The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date.
        Parameters:
        lastReviewDate - When the effect evidence synthesis was last reviewed
        Returns:
        A reference to this Builder instance
      • effectivePeriod

        public EffectEvidenceSynthesis.Builder effectivePeriod​(Period effectivePeriod)
        The period during which the effect evidence synthesis content was or is planned to be in active use.
        Parameters:
        effectivePeriod - When the effect evidence synthesis is expected to be used
        Returns:
        A reference to this Builder instance
      • topic

        public EffectEvidenceSynthesis.Builder topic​(CodeableConcept... topic)
        Descriptive topics related to the content of the EffectEvidenceSynthesis. Topics provide a high-level categorization grouping types of EffectEvidenceSynthesiss that can be useful for filtering and searching.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        topic - The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc.
        Returns:
        A reference to this Builder instance
      • topic

        public EffectEvidenceSynthesis.Builder topic​(Collection<CodeableConcept> topic)
        Descriptive topics related to the content of the EffectEvidenceSynthesis. Topics provide a high-level categorization grouping types of EffectEvidenceSynthesiss that can be useful for filtering and searching.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        topic - The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc.
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • author

        public EffectEvidenceSynthesis.Builder author​(ContactDetail... author)
        An individiual or organization primarily involved in the creation and maintenance of the content.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        author - Who authored the content
        Returns:
        A reference to this Builder instance
      • author

        public EffectEvidenceSynthesis.Builder author​(Collection<ContactDetail> author)
        An individiual or organization primarily involved in the creation and maintenance of the content.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        author - Who authored the content
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • editor

        public EffectEvidenceSynthesis.Builder editor​(ContactDetail... editor)
        An individual or organization primarily responsible for internal coherence of the content.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        editor - Who edited the content
        Returns:
        A reference to this Builder instance
      • editor

        public EffectEvidenceSynthesis.Builder editor​(Collection<ContactDetail> editor)
        An individual or organization primarily responsible for internal coherence of the content.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        editor - Who edited the content
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • reviewer

        public EffectEvidenceSynthesis.Builder reviewer​(ContactDetail... reviewer)
        An individual or organization primarily responsible for review of some aspect of the content.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        reviewer - Who reviewed the content
        Returns:
        A reference to this Builder instance
      • reviewer

        public EffectEvidenceSynthesis.Builder reviewer​(Collection<ContactDetail> reviewer)
        An individual or organization primarily responsible for review of some aspect of the content.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        reviewer - Who reviewed the content
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • endorser

        public EffectEvidenceSynthesis.Builder endorser​(ContactDetail... endorser)
        An individual or organization responsible for officially endorsing the content for use in some setting.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        endorser - Who endorsed the content
        Returns:
        A reference to this Builder instance
      • endorser

        public EffectEvidenceSynthesis.Builder endorser​(Collection<ContactDetail> endorser)
        An individual or organization responsible for officially endorsing the content for use in some setting.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        endorser - Who endorsed the content
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • relatedArtifact

        public EffectEvidenceSynthesis.Builder relatedArtifact​(RelatedArtifact... relatedArtifact)
        Related artifacts such as additional documentation, justification, or bibliographic references.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        relatedArtifact - Additional documentation, citations, etc.
        Returns:
        A reference to this Builder instance
      • relatedArtifact

        public EffectEvidenceSynthesis.Builder relatedArtifact​(Collection<RelatedArtifact> relatedArtifact)
        Related artifacts such as additional documentation, justification, or bibliographic references.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        relatedArtifact - Additional documentation, citations, etc.
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • synthesisType

        public EffectEvidenceSynthesis.Builder synthesisType​(CodeableConcept synthesisType)
        Type of synthesis eg meta-analysis.
        Parameters:
        synthesisType - Type of synthesis
        Returns:
        A reference to this Builder instance
      • population

        public EffectEvidenceSynthesis.Builder population​(Reference population)
        A reference to a EvidenceVariable resource that defines the population for the research.

        This element is required.

        Allowed resource types for this reference:

        Parameters:
        population - What population?
        Returns:
        A reference to this Builder instance
      • exposure

        public EffectEvidenceSynthesis.Builder exposure​(Reference exposure)
        A reference to a EvidenceVariable resource that defines the exposure for the research.

        This element is required.

        Allowed resource types for this reference:

        Parameters:
        exposure - What exposure?
        Returns:
        A reference to this Builder instance
      • exposureAlternative

        public EffectEvidenceSynthesis.Builder exposureAlternative​(Reference exposureAlternative)
        A reference to a EvidenceVariable resource that defines the comparison exposure for the research.

        This element is required.

        Allowed resource types for this reference:

        Parameters:
        exposureAlternative - What comparison exposure?
        Returns:
        A reference to this Builder instance
      • outcome

        public EffectEvidenceSynthesis.Builder outcome​(Reference outcome)
        A reference to a EvidenceVariable resomece that defines the outcome for the research.

        This element is required.

        Allowed resource types for this reference:

        Parameters:
        outcome - What outcome?
        Returns:
        A reference to this Builder instance
      • resultsByExposure

        public EffectEvidenceSynthesis.Builder resultsByExposure​(EffectEvidenceSynthesis.ResultsByExposure... resultsByExposure)
        A description of the results for each exposure considered in the effect estimate.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        resultsByExposure - What was the result per exposure?
        Returns:
        A reference to this Builder instance
      • resultsByExposure

        public EffectEvidenceSynthesis.Builder resultsByExposure​(Collection<EffectEvidenceSynthesis.ResultsByExposure> resultsByExposure)
        A description of the results for each exposure considered in the effect estimate.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Parameters:
        resultsByExposure - What was the result per exposure?
        Returns:
        A reference to this Builder instance
        Throws:
        NullPointerException - If the passed collection is null
      • effectEstimate

        public EffectEvidenceSynthesis.Builder effectEstimate​(EffectEvidenceSynthesis.EffectEstimate... effectEstimate)
        The estimated effect of the exposure variant.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        effectEstimate - What was the estimated effect
        Returns:
        A reference to this Builder instance
      • certainty

        public EffectEvidenceSynthesis.Builder certainty​(EffectEvidenceSynthesis.Certainty... certainty)
        A description of the certainty of the effect estimate.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Parameters:
        certainty - How certain is the effect
        Returns:
        A reference to this Builder instance