Class SubstanceProtein.Subunit.Builder

    • Method Detail

      • id

        public SubstanceProtein.Subunit.Builder id​(java.lang.String id)
        Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
        Overrides:
        id in class BackboneElement.Builder
        Parameters:
        id - Unique id for inter-element referencing
        Returns:
        A reference to this Builder instance
      • extension

        public SubstanceProtein.Subunit.Builder extension​(Extension... extension)
        May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Overrides:
        extension in class BackboneElement.Builder
        Parameters:
        extension - Additional content defined by implementations
        Returns:
        A reference to this Builder instance
      • extension

        public SubstanceProtein.Subunit.Builder extension​(java.util.Collection<Extension> extension)
        May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Overrides:
        extension in class BackboneElement.Builder
        Parameters:
        extension - Additional content defined by implementations
        Returns:
        A reference to this Builder instance
        Throws:
        java.lang.NullPointerException - If the passed collection is null
      • modifierExtension

        public SubstanceProtein.Subunit.Builder modifierExtension​(Extension... modifierExtension)
        May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

        Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

        Adds new element(s) to the existing list. If any of the elements are null, calling build() will fail.

        Overrides:
        modifierExtension in class BackboneElement.Builder
        Parameters:
        modifierExtension - Extensions that cannot be ignored even if unrecognized
        Returns:
        A reference to this Builder instance
      • modifierExtension

        public SubstanceProtein.Subunit.Builder modifierExtension​(java.util.Collection<Extension> modifierExtension)
        May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

        Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

        Replaces the existing list with a new one containing elements from the Collection. If any of the elements are null, calling build() will fail.

        Overrides:
        modifierExtension in class BackboneElement.Builder
        Parameters:
        modifierExtension - Extensions that cannot be ignored even if unrecognized
        Returns:
        A reference to this Builder instance
        Throws:
        java.lang.NullPointerException - If the passed collection is null
      • subunit

        public SubstanceProtein.Subunit.Builder subunit​(java.lang.Integer subunit)
        Convenience method for setting subunit.
        Parameters:
        subunit - Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts
        Returns:
        A reference to this Builder instance
        See Also:
        subunit(com.ibm.fhir.model.type.Integer)
      • subunit

        public SubstanceProtein.Subunit.Builder subunit​(Integer subunit)
        Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts.
        Parameters:
        subunit - Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts
        Returns:
        A reference to this Builder instance
      • sequence

        public SubstanceProtein.Subunit.Builder sequence​(java.lang.String sequence)
        Convenience method for setting sequence.
        Parameters:
        sequence - The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single- letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence
        Returns:
        A reference to this Builder instance
        See Also:
        sequence(com.ibm.fhir.model.type.String)
      • sequence

        public SubstanceProtein.Subunit.Builder sequence​(String sequence)
        The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single- letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.
        Parameters:
        sequence - The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single- letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence
        Returns:
        A reference to this Builder instance
      • length

        public SubstanceProtein.Subunit.Builder length​(Integer length)
        Length of linear sequences of amino acids contained in the subunit.
        Parameters:
        length - Length of linear sequences of amino acids contained in the subunit
        Returns:
        A reference to this Builder instance
      • sequenceAttachment

        public SubstanceProtein.Subunit.Builder sequenceAttachment​(Attachment sequenceAttachment)
        The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single- letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.
        Parameters:
        sequenceAttachment - The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single- letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence
        Returns:
        A reference to this Builder instance
      • nTerminalModificationId

        public SubstanceProtein.Subunit.Builder nTerminalModificationId​(Identifier nTerminalModificationId)
        Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID.
        Parameters:
        nTerminalModificationId - Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID
        Returns:
        A reference to this Builder instance
      • nTerminalModification

        public SubstanceProtein.Subunit.Builder nTerminalModification​(java.lang.String nTerminalModification)
        Convenience method for setting nTerminalModification.
        Parameters:
        nTerminalModification - The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified
        Returns:
        A reference to this Builder instance
        See Also:
        nTerminalModification(com.ibm.fhir.model.type.String)
      • nTerminalModification

        public SubstanceProtein.Subunit.Builder nTerminalModification​(String nTerminalModification)
        The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified.
        Parameters:
        nTerminalModification - The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified
        Returns:
        A reference to this Builder instance
      • cTerminalModificationId

        public SubstanceProtein.Subunit.Builder cTerminalModificationId​(Identifier cTerminalModificationId)
        Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID.
        Parameters:
        cTerminalModificationId - Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID
        Returns:
        A reference to this Builder instance
      • cTerminalModification

        public SubstanceProtein.Subunit.Builder cTerminalModification​(String cTerminalModification)
        The modification at the C-terminal shall be specified.
        Parameters:
        cTerminalModification - The modification at the C-terminal shall be specified
        Returns:
        A reference to this Builder instance